听力与言语-语言病理学

行为科学

医学伦理学

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  • Screening for xenobiotic electrophilic metabolites using pulsed ultrafiltration-mass spectrometry.

    abstract::A pulsed ultrafiltration-mass spectrometric screening assay has been developed to generate and identify electrophilic metabolites of xenobiotic compounds formed by hepatic cytochrome P450 enzymes. This assay would be suitable for the early identification of potentially toxic compounds during the initial phase of drug ...

    journal_title:Combinatorial chemistry & high throughput screening

    pub_type: 杂志文章

    doi:

    authors: Nikolic D,Fan PW,Bolton JL,van Breemen RB

    更新日期:1999-06-01 00:00:00

  • Combinatorial libraries: studies in molecular recognition.

    abstract::In recent years, combinatorial libraries have become a major tool for drug discovery and drug development. Along the way, one potential use of combinatorial chemistry libraries almost been neglected: the basic study of intermolecular interactions. Especially "one-bead-one-structure" libraries can be a powerful means f...

    journal_title:Combinatorial chemistry & high throughput screening

    pub_type: 杂志文章,评审

    doi:

    authors: Nestler HP,Liu R

    更新日期:1998-10-01 00:00:00

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